Arthritis: Mind →Body - Neurophysiological Chain

 

Series - Science with Spirituality- Blog3/5

Mind: Negative Perception & Repetitive Thought

• External trigger: difficult circumstances (financial stress, lack of recognition, social burden).
• Internal thought: “I am unable to move forward in life as I wish.”
• With repetition, this becomes a Repetitive Internal Dominant Focus (IDF) — the mind keeps looping on limitation and immobility.

2. Subconscious Filter: Acceptance of Limitation

• The subconscious accepts this thought-frequency as truth.
• Synapses in stress-related circuits (amygdala, hippocampus, prefrontal cortex) reinforce the negative pattern.
• Over time, neural plasticity strengthens the “immobility” pathway.

3. Neurotransmitter Imbalance: Stress Circuits

• Chronic stress reduces dopamine and serotonin, lowering motivation and mood.
• Excess glutamate and norepinephrine heighten stress reactivity.
• GABA (the calming neurotransmitter) becomes suppressed, leading to tension.

4. Hypothalamic Activation: Neuro-Endocrine Link

• The hypothalamus detects the “threat” from these repeated signals.
• It activates the HPA axis (Hypothalamus–Pituitary–Adrenal system

5. Hormonal Response: Cortisol Release

• The pituitary signals the adrenal glands to release cortisol.
• In acute stress, cortisol is protective.
• In chronic stress, persistent cortisol release causes immune dysregulation.

6. Immune Activation: Inflammatory Pathways

• Cortisol imbalance alters immune cell signaling.
• The immune system mistakenly triggers inflammatory cytokines (IL-1, IL-6, TNF-α).
• These cytokines target connective tissues, cartilage, and synovial linings of joints.

7. Physical Manifestation: Arthritis

• Inflammation sets into joint capsules (hands, knees, hips).
• Cartilage breakdown occurs over time.
• The patient experiences pain, stiffness, swelling, and restricted mobility.

✨ Summary Flow

Repetitive IDF (“I cannot move forward”) → Synaptic filtering → Neurotransmitter imbalance → HPA axis activation → Cortisol dysregulation → Immune inflammation → Joint damage → Arthritis.

In clinical version - 

1. External Circumstance
   
• Difficult situations (financial stress, lack of recognition, overwhelming responsibilities).
2. 
   
3. Negative Thought (Mind)
   
• “I cannot move forward in life.”
4. 
   
5. Low-Frequency Emotion (Energy)
   
• Frustration, helplessness, burden.
• These emotions vibrate at a low frequency, draining motivation.
6. 
   
7. Repetitive Internal Dominant Focus (Subconscious)
   
• The subconscious locks onto this emotion daily: “Movement is blocked.”
8. 
   
9. Neurotransmitter Imbalance (Brain)
   
• ↓ Dopamine & Serotonin → less joy, less motivation.
• ↑ Glutamate & Norepinephrine → heightened stress.
10. 
    
11. HPA Axis Activation (Neuro-Endocrine)
    
• Hypothalamus → Pituitary → Adrenal glands → Cortisol released continuously.
12. 
    
13. Immune Dysregulation
    
• Chronic cortisol disrupts immune balance.
• Cytokines (IL-1, IL-6, TNF-α) trigger joint inflammation.
14. 
    
15. Physical Manifestation
    
• Joints (organs of movement) swell, stiffen, and weaken.
• Arthritis symptoms: pain, immobility, stiffness

✨ Body mirrors subconscious truth: “If I cannot move forward in life, I cannot move freely in body.”

To heal arthritis or cope with arteries , this belief has to be changed with cognitive consent .

Reference- Shiva Swati - How to be happy in difficulties , a soul’s perspective 

Important Note on Triggers

External factors such as allergens, infections, pollution, deficiencies, or physical stressors are often cited as causes of disease. However, they do not create the same reactions in every individual. According to the present model, these external triggers only lead to chronic dysfunction when the neurophysiological chain is already primed by a negative Internal Dominant Focus (IDF) that resonates with the organ’s emotional function. Without this subconscious resonance, the body can often neutralize the trigger without developing disease.

Equally important is the role of healing: when the neurophysiological cause is addressed through mindfulness, positive reinforcement, regression therapy, or other methods that shift the Internal Dominant Focus toward positivity, the disease can gradually resolve. In such cases, medicines and alternative therapies also work more effectively, as the underlying vibrational frequency is no longer reinforcing the dysfunction.

• Arthritis: Nutritional deficiencies or aging may affect joints, but chronic arthritis arises when the IDF “I cannot move forward” resonates with the joints. Mindfulness and regression therapy can reframe this into “I move freely in life,” reducing inflammation and enhancing medical treatment outcomes.